Monkeypox treatment trial begins in the Democratic Republic of the NIH partnering with INRB to evaluate tecovirimat (TPOXX). National Institutes of Health (NIH)

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The trial will evaluate the drug’s safety and its ability to mitigate monkeypox symptoms and prevent serious outcomes, including death.

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Monkeypox response looks to long term - Roll Call Federal officials warn that monkeypox is here to stay, but hope to use a combination of strategies to limit the spread of the virus. Roll Call

Federal officials look to vaccines, treatment, education to limit spread

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Covid cases rise as one in 37 has virus in UK The estimates show there has been a "notable rise" in infections older people in England and Wales. BBC News

The latest estimates from the Office for National Statistics (ONS) suggest one in 37 people in the UK has coronavirus, a rise from one in 50 the week before.

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German health minister urges stepped-up COVID-19 measures BERLIN (AP) — Germany's health minister on Friday urged the country's 16 states to consider stepping up their measures against the coronavirus amid a rise in new cases. Health Minister Karl Lauterbach said he favors requiring mask-wearing indoors, a measure that has largely faded in Germany except on public transport, in medical facilities and care homes. AP NEWS

...“The direction we’re going in isn’t a good one,” Lauterbach told reporters in Berlin.

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The last Covid holdouts in Asia are throwing open their doors for travel -- except for China Across Asia, borders are opening and quarantine measures are lifting as even the last few countries clinging to Covid restrictions embrace a return to travel. By Jessie Yeung, CNN CNN

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But in China -- which has seen its own economy suffer from a strict zero-Covid policy involving tight border controls, snap lockdowns and mandatory quarantines -- there appears to be no end in sight to the restrictions, despite mounting public frustration.

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Vaccine trials on Sudan Ebola strain to start in weeks - WHO chief World Health Organization chief Tedros Adhanom Ghebreyesus said on Wednesday a clinical trial of vaccines to combat the Sudan strain of Ebola could start within weeks as an outbreak of the disease in Uganda reached the capital, stirring alarm. Elias Biryabarema Reuters

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In drawn-out recovery, NYC inches out from COVID's shadow NEW YORK (AP) — As kids returned to school last month, people watching New York City pull itself out of COVID-19's shadow wondered whether workers who fled Manhattan's office towers during the pandemic would finally return in a rush, too. AP NEWS

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Pfizer, BioNTech's updated booster protects against Omicron in human trial Pfizer and its German partner BioNTech said their COVID-19 vaccine booster, adapted for the BA.4 and the BA.5 subvariants, generated a strong immune response and was well tolerated in testing on humans. Ludwig Burger,Manas Mishra Reuters

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What Covid-19 precautions should people take for international travel? Last week, the US Centers for Disease Control and Prevention announced it would no longer be maintaining a country-by-country travel advisory of Covid-19 risk. Instead of assessing the level of Covid-19 infection in each country, the CDC will post notices only when there are new variants or other situations that would change its travel recommendations. By Katia Hetter, CNN CNN

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Haiti risks new diseases amid cholera outbreak that has killed 18, says PAHO Civil unrest is making it harder to contain a new outbreak of cholera in Haiti just as other diseases threaten to ignite new health crises, the Pan American Health Organization (PAHO) said Wednesday. Reuters Reuters

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Covid-19 treatment Paxlovid can interact with common heart medications, doctors warn | CNN Covid-19 patients with a history of cardiovascular disease are at an increased risk of developing severe illness and could benefit most from the Covid-19 treatment Paxlovid -- but there's a catch. Jacqueline Howard CNN

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Paxlovid can have dangerous interactions with some of the most common medications for cardiovascular disease, including certain statins and heart failure therapies, a new paper warns.

Novavax says COVID booster dose shows benefit against Omicron variants Novavax Inc said on Wednesday data from studies in adults and adolescents showed that the booster dose of its COVID vaccine produced robust antibodies against several Omicron variants, including BA.1, BA.2 and BA.5. Reuters Reuters

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FDA clears updated COVID boosters for kids as young as 5 The U.S. on Wednesday authorized updated COVID-19 boosters for children as young as 5, seeking to expand protection ahead of an expected winter wave. Tweaked boosters rolled out for Americans 12 and older last month, doses modified to target today’s most common and contagious omicron relative . AP NEWS

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There’s one more step before parents can bring their kids in for the new shot: The Centers for Disease Control and Prevention, which recommends how vaccines are used, must sign off.

Myocarditis, pericarditis remains rare after COVID-19 booster Myocarditis and pericarditis after COVID-19 vaccination is rare across demographic groups and most likely to occur in teen boys in the week after their second shot of a two-dose vaccine, according to a study.

Myocarditis and pericarditis after COVID-19 vaccination is rare across demographic groups and most likely to occur in teen boys in the week after their second shot of a two-dose vaccine, according to a study.