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Ebola gene study traces origin of current outbreak

- 29 August 2014 - medicalnewstoday.com

An international research team has rapidly sequenced 99 Ebola virus genomes collected in the 2014 outbreak. The team, including members from the Broad Institute and Harvard University in the US and the Sierra Leone Ministry of Health and Sanitation, hopes the findings will help multidisciplinary, international efforts to understand and contain the unprecedented epidemic that is growing in West Africa.

The researchers report their findings in the journal Science. Five team members died of Ebola virus disease before the manuscript was published, and their fellow authors honor their memory in the study report.

The 99 genomes came from 78 patients diagnosed with Ebola virus disease in Sierra Leone during the first 24 days of the outbreak. Some patients gave more than one sample, allowing the team to see how the virus changed over the course of a single infection.

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Cell-Phone Data Might Help Predict Ebola’s Spread

On the move: This model of West African regional transportation patterns was built using, among other sources, mobile-phone data for Senegal, released by the mobile carrier Orange.

Mobility data from an African mobile-phone carrier could help researchers recommend where to focus health-care efforts.

By David Talbot on August 22, 2014

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Ebola spreads to Nigeria oil hub Port Harcourt

More than 240 health workers have been infected with Ebola in West AfricaBBC News -

Nigeria has confirmed its first Ebola death outside Lagos – a doctor in the oil hub of Port Harcourt.  His wife has been put under quarantine, while a further 70 people in the city are under surveillance.  Latest figures show more than 1,550 people have died of Ebola, with at least 3,000 confirmed cases - mostly in Guinea, Liberia and Sierra Leone.  The World Health Organization (WHO) estimates that the total number of cases could potentially exceed 20,000.

http://www.bbc.com/news/world-africa-28966258

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Ebola outbreak: Why Liberia's quarantine in West Point slum will fail

A relic of the Middle Ages, quarantines do more harm than good

By Amber Hildebrandt, CBC News Aug 25, 2014 5:00 AM ET

Medical experts say that mass quarantine is rarely if ever effective in stemming the spread of a contagion like Ebola, and the move by Liberia to cordon off a sprawling slum is likely to do more harm than good.

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Fears Held Over Ebola's Spread in Worst-Ever Outbreak

      

There are fears Ebola has spread to a fifth country, the Democratic Republic of Congo, as sub-Saharan African authorities take drastic steps to keep population centres safe from the worst-ever Ebola outbreak.

Australian Broadcasting Corporation - Broadcast: 25/08/2014 - Reporter: Martin Cuddihy

. . . GAVIN MACGREGOR-SKINNER, ELIZABETH R. GRIFFIN RESEARCH FOUNDATION: It's heartbreaking. For being involved in infectious diseases prevention and control for years, what I'm hearing on the news, what I'm reading and the conversations that I'm having with colleagues in West Africa, it's absolutely heartbreaking.

MARTIN CUDDIHY: Gavin MacGregor-Skinner is an Australian expert in public health and emergency responses. He's now based in Washington, DC, but is preparing to leave for Nigeria. He says technology is making a big difference in how quickly authorities can react.

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Ebola - Aligned Organizations

The following is a list of aligned organizations for Ebola response . . .

Mission Aviation Fellowship (MAF) - John Boyd, CEO
http://www.maf.org/

King's Sierra Leone Partnership (KSLP) Ebola Response Volunteers
http://kslp.org.uk/get-involved/lend-your-skills/ebola-volunteers/

Minnesotans offer helping hands, aid at epicenter of Ebola outbreak
http://www.startribune.com/lifestyle/health/271472521.html

Global Health Ministries - Ebola Outbreak Response Shipments (photos at the bottom)
http://www.ghm.org/index.php/liberia/57-projects/277-ebola-outbreak-response-shipments

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Clashes Erupt as Liberia Sets an Ebola Quarantine

AUG. 20, 2014

The New York Times

MONROVIA, Liberia — Soldiers and police officers in riot gear blocked the roads. Even the waterfront was cordoned off, with the coast guard stopping residents from setting out in canoes. The entire neighborhood, a sprawling slum with tens of thousands of people, awoke Wednesday morning to find that it was under strict quarantine in the government’s halting fight against Ebola.

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Boots on the Ground

Bloomberg School students assess Ebola interventions at outbreak epicenter.

When the Red Cross asked for help conducting Ebola-related research in Guinea, Bloomberg School doctoral students Tim Roberton and Clementine Fu immediately stepped forward. From July 19 to August 1, the two worked in the outbreak’s initial epicenter in Guéckédou, and in the capital city of Conakry.

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Liberia President Declares Ebola Curfew

      

In this undated handout photo provided by Medecins Sans Frontieres, local staff and healthcare workers for Doctors Without Borders, exit an isolation ward in Guekedou, Guinea. For doctors and nurses fighting Ebola in West Africa, working in head-to-toe protective gear in muddy health clinics is often the least of their problems, as many also struggle to convince people they are there to stop Ebola, not spread it. (AP Photo/MSF)

ap.org - by JONATHAN PAYE-LAYLEH - August 19, 2014

MONROVIA, Liberia (AP) -- Liberia's president declared a curfew and ordered security forces to quarantine a slum home to at least 50,000 people late Tuesday as the West African country battled to stop the spread of Ebola in the capital. . .

. . . Liberian President Ellen Johnson Sirleaf announced late Tuesday that a curfew is going into place from 9 p.m. to 6 a.m. Security forces also will be ensuring no one goes in or out of West Point, a slum in the capital where angry residents attacked an Ebola observation center over the weekend.

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Ebola Crisis: 3 Receiving Untested Ebola Drug in Liberia Improving

      

A girl suspected of being infected with the Ebola virus has her temperature checked at the government hospital in Kenema, Sierra Leone. Although the outbreak began in Guinea, Liberia has now recorded the highest number of deaths and Sierra Leone the most cases. (Carl de Souza/AFP/Getty)

Ebola situation is 'less alarming' in Guinea than it is in Liberia and Sierra Leone, WHO says

cbc.ca - Associated Press - August 19, 2014

Three Liberian health workers receiving an experimental drug for Ebola are showing signs of recovery, officials said Tuesday, though medical experts caution it is not certain if the drug is effective. . .

. . . The three Liberians are being treated with the last known doses of ZMapp, a drug that had earlier been given to two infected Americans and a Spaniard. The Americans are also improving, but the Spaniard died.

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