Public Health - Conakry

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Tue, 2013-09-10 02:11 — mdmcdonald

This working group is focused on discussions about public health.

The mission of this working group is to focus on discussions about public health.

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Aboubacar Conte	Anthony	Elhadj Drame	Hadiatou Balde	Kathy Gilbeaux	mdmcdonald
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Assessing the Potential Role of Pigs in the Epidemiology of Ebola Virus in Uganda

Wed, 2015-09-02 17:00 — Kathy Gilbeaux

Ebolavirus, animal - Uganda: porcine, epidemiological assessment

CLICK HERE - Assessing the Potential Role of Pigs in the Epidemiology of Ebola Virus in Uganda

promedmail.org - September 2, 2015

Summary

Uganda has experienced 4 Ebola outbreaks since the discovery of the virus. Recent epidemiological work has shown pigs are hosts for ebolaviruses. Due to their high reproduction rates, rapid weight gain, potential to provide quick financial returns, and rising demand for pork, pig production in Uganda has undergone massive expansion. The combination of pork sector growth supported by development programmes and Ebola virus risk prompted a foresight exercise using desk, interview, and spatial methods. The study found that the lack of serological evidence for specific reservoir species, the number of human index cases unable to account for their source of infection, domestic pig habitat overlap with potential Ebola virus zoonotic host environments, reported interactions at the human-pig-wildlife interface that could support transmission, fever in pigs as a commonly reported problem by pig farmers, and temporal correlation of outbreaks with peak pork consumption periods, warrants further research into potential zoonotic transmission in Uganda from pigs.

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Mano River Union (MRU) Countries Recommend Information Sharing

Tue, 2015-09-01 20:52 — Kathy Gilbeaux

thenewdawnliberia.com - by Ben P. Wesee - Editing by Jonathan Browne -September 1, 2015

The four Mano River Union or MRU countries – Liberia, Sierra Leone, Guinea and Ivory Coast have issued a joint communiqué in Monrovia, calling for information sharing, experiences and good practices during and after health emergencies in order to collaborate and network with local and international partners in the sub-region.

In a just ended conference here on the Ebola Virus Disease or EVD, the MRU countries also advanced several recommendations. Delegates from the four countries recommended in the communiqué a need to develop a harmonized framework for adherence to ethical standards during health disasters with appropriate and approved mechanisms for vaccines, therapeutic agents and testing methods.

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(ALSO SEE RELATED ARTICLE HERE)

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Interagency Collaboration on Ebola - Situation Report - 1 September 2015

Tue, 2015-09-01 19:58 — Kathy Gilbeaux

Ebola Situation Reports:

CLICK HERE - Interagency Collaboration on Ebola - Situation Report - 1 September 2015 (7 page .PDF report)

CLICK HERE - Report Archives - Interagency Collaboration on Ebola

Note:

The numbers of suspected Ebola cases have increased by 2 in Guinea, and by 6 in Sierra Leone per the Aug. 30 data as compared to the August 29 data.

August 30 data (Published September 1)
http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-20150901?lang=en

August 29 data (Published August 31)
http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-20150831?lang=en

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Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax

Tue, 2015-09-01 19:23 — Kathy Gilbeaux

CLICK HERE - RESEARCH - Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

prweb.com - by Cynthia Lujan - September 1, 2015

A new host-based therapy for Ebola, anthrax and other deadly infectious diseases has been discovered by researchers at the Keck Graduate Institute and its collaborators. The discovery has the potential to speed to market treatments for previously untreatable diseases.

The findings were published online on August 27 by Scientific Reports, an open access research journal from the publishers of Nature.

The lead authors of the story were Leoor Zilberminitz and William Leonardi, doctoral students in KGI laboratory of assistant professor Mikhail Martchenko. The researchers screened a library of 1,581 drugs previously approved by the FDA for in vitro protection of mammalian cells against Bacillus anthracis lethal toxin and diphtheria toxin, which normally kill 50-70% of unprotected cells. They then investigated the 1% most promising compounds that both provided the best protection against the two toxins and were not toxic to uninfected cells.

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Sierra Leone: Officials Confirm New Ebola Death 6 Days After Discharging Last Known Patient

Sun, 2015-08-30 18:57 — Kathy Gilbeaux

usnews.com - Associated Press (AP) - by CLARENCE ROY-MACAULAY - August 30, 2015

FREETOWN, Sierra Leone (AP) — Health officials in Sierra Leone on Sunday confirmed an Ebola death less than a week after the country's last known patient was discharged from a hospital.

Samples from the body of a 67-year-old woman who died recently in Kambia district in the country's north came back positive for the deadly disease, said chief medical officer Dr. Brima Kargbo. . . .

. . . The National Ebola Response Center had deployed teams to conduct surveillance and trace people who were in contact with the woman, said OB Sisay, the center's director.

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Guinea Extends Ebola Ring Vaccine Trial to Sierra Leone

Fri, 2015-08-28 03:09 — Kathy Gilbeaux

allafrica.com - August 24, 2015

Freetown — The Guinean Ebola Ring Vaccine Trial has been extended to Sierra Leone as a move to stop the transmission across the region.

Addressing participants in the opening ceremony of the training session at the Brookfields Hotel Conference Hall in Freetown, the WHO Ebola Technical Coordinator Sierra Leone, Dr. Margaret Lamumu said prior to the extension of the vaccine to Sierra Leone the Ministry of Health and Sanitation and WHO Joint Team visited five sites to make available the vaccine study, adding that expert trainers from the UK were targeted to do the training. . . .

. . . The Chief Medical Officer, Dr. Brima Kargbo said the use of the vaccine would help break the chain of transmission, stressing the need to work collectively as a team to control the spread of the disease.

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(CLICK HERE - For Additional Information)

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CDC Updates Ebola PPE Guidance for U.S. Health Care Facilities

Fri, 2015-08-28 02:34 — Kathy Gilbeaux

CDC - American Hospital Association - August 27, 2015

The Centers for Disease Control and Prevention today issued updated guidance regarding personal protective equipment for health care personnel caring for suspected and confirmed Ebola patients in U.S. health care facilities. The changes clarify the use of fluid-resistant and impermeable gowns and coveralls, and provide specifications to assist facilities in selecting and ordering the recommended garments. The updates also provide additional explanation related to PPE for confirmed Ebola patients. For more information, see the updated PPE Frequently Asked Questions.

http://news.aha.org/article/150827-cdc-updates-ebola-ppe-guidance-for-us-health-care-facilities

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Interagency Collaboration on Ebola - Situation Report - 25-26 August 2015 - WHO

Thu, 2015-08-27 12:55 — Kathy Gilbeaux

Ebola Situation Reports:

CLICK HERE - Interagency Collaboration on Ebola - Situation Report - 25 August 2015 (7 page .PDF report)

CLICK HERE - WHO - Situation Report - 26 August 2015

CLICK HERE - Report Archives - Interagency Collaboration on Ebola

CLICK ON THE LINKS BELOW - Current - Report Archives - WHO
http://apps.who.int/ebola/ebola-situation-reports
http://apps.who.int/ebola/ebola-situation-reports-archive

CLICK ON THE LINK BELOW - Older Report Archives - WHO
http://www.who.int/csr/disease/ebola/situation-reports/archive/en/

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Antiviral Drug May Prevent Ebola, Small Study Suggests

Thu, 2015-08-27 11:30 — Kathy Gilbeaux

Health care workers deemed at high risk for infection didn't get sick after treatment with anti-flu regimen

CLICK HERE - The Lancet - Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers

nlm.nih.gov - by Robert Preidt - August 25, 2015

Antiviral drugs may help protect people from developing Ebola after exposure to the deadly virus, a new case study suggests.

"We are excited to publish the first report of an antiviral-based post-exposure treatment against Ebola-virus infection in humans. We believe this work justifies further study of this postexposure treatment to protect health care workers accidentally exposed to Ebola virus in the field," lead author Dr. Michael Jacobs, of the Royal Free NHS Foundation Trust, London, said in a news release from The Lancet Infectious Diseases.

"What is more, a similar approach to treat household contacts of Ebola cases may work to prevent a major route of spread during an epidemic," he added.

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Assessing the Evidence Supporting Fruit Bats as the Primary Reservoirs for Ebola Viruses

Thu, 2015-08-27 11:00 — Kathy Gilbeaux

link.springer.com - EcoHealth - August 13, 2015
Siv Aina J. Leendertz, Jan F. Gogarten, Ariane Düx, Sebastien Calvignac-Spencer, Fabian H. Leendertz

CLICK HERE - Assessing the Evidence Supporting Fruit Bats as the Primary Reservoirs for Ebola Viruses

Introduction

Since their discovery 40 years ago, Ebola viruses (in the following: EBOV; family Filoviridae, genus Ebolavirus) continue to emerge unpredictably and cause Ebola virus disease (EVD) in humans and susceptible animals in tropical Africa (Leroy et al. 2004; Feldmann and Geisbert 2011). The scale of the current epidemic in West Africa demonstrates the impact that a single spillover event can have (Baize et al. 2014; Gire et al. 2014). Meanwhile, the reservoir(s) and ecology of EBOV remain largely unknown (Groseth et al. 2007; Feldmann and Geisbert 2011), hampering prediction of future outbreaks.

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