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NIH Study Finds No Evidence of Accelerated Ebola Virus Evolution in West Africa

NIH Institute of Allergy and Infectious Diseases (NIAID)                            June 9, 2015

According to a recent report from the National Institutes of Health (NIH), the current strain of the Ebola virus that is circulating through West Africa is called the Makona strain and is less aggressive than the original Mayinga strain that, which was isolated in Central Africa in 1976.
When compared to the Mayinga strain, the Makona strain takes approximately two additional days to start terminal disease in an animal subject. This is an important discovery to scientists, as they wonder whether the Ebola strain in West Africa will grow more severe over time.

The test subjects were cynomolgus macaques. Researchers used these animals to model disease and infection in humans. The scientists infected three macaques with the Mayinga strain from 1976 and an additional three with the Makona strain from 2015.

 
 Ebola virus, isolated in November 2014 from patient blood samples obtained in Mali. The virus was isolated on Vero cells in a BSL-4 suite at Rocky Mountain Laboratories.
Credit: NIAID RML

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Akon Launches Solar Academy That Will Supply Electricity to 600,000,000 People in Africa

Photo: Denis Van Tine/AP Photo

The musician is giving back to people in a major way.

theroot.com - by Yesha Callahan - June 2, 2015

When he’s not singing or producing music, Akon is busy providing sustainable living options to people in African countries. The Senegalese-American singer’s initiative, appropriately called Akon Lighting Africa, aims to supply electricity to 600 million people in Africa who lack it with the launch of the Solar Academy.

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G7 states vow to wipe out Ebola but offer little concrete action

REUTERS                                                      June 8, 2015

KRUEN, Germany - Leaders of the Group of Seven industrial nations pledged on Monday to wipe out Ebola but offered little in terms of concrete action, disappointing non-governmental organisations.

G7 leaders said in a communique at the end of a two-day summit in the Bavarian Alps that they would offer help to at least 60 nations, including in West Africa, over the next five years to help prevent outbreaks from turning into epidemics.

More than 11,000 people have died in the Ebola outbreak in West Africa since the first reported case in March 2014. The G7 said the crisis showed it was necessary to enhance the world's ability to prevent, detect and respond to such emergencies.

The G7 nations said they would work together to combat future epidemics and boost or establish strategies to quickly deploy teams of experts with a variety of skills via a common platform, but their communique was thin on detail.

Florian Westphal, General Director of Medecins Sans Frontieres (MSF) Germany, said the leaders had done little to ensure epidemics would not spiral out of control in future....

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Transmission Models of Historical Ebola Outbreaks

CDC,  by John Drake and others Volume 21, Number 8—August 2015

 To guide the collection of data under emergent epidemic conditions, we reviewed compartmental models of historical Ebola outbreaks to determine their implications and limitations. We identified future modeling directions and propose that the minimal epidemiologic dataset for Ebola model construction comprises duration of incubation period and symptomatic period, distribution of secondary cases by infection setting, and compliance with intervention recommendations....

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How Mobile Technology Is Bringing Trauma Relief After Ebola

SINGULARITY HUB   by Nathan and Elie Calhoun                                                   June , 2015

....the promise of mobile technology is that we can connect the farthest, most remote corners of the globe to the Internet—where a treasure trove of information and applications can be had nearly for free.

 For aid workers, this technology is proving a powerful, even revolutionary tool.

We hope our new community mental health app will demonstrate a new depth of potential impact.

When we started designing our psychosocial services app for Liberian communities recently ravaged by Ebola, we thought we’d first need to justify the very idea of focusing on mental health in a country facing so many pressing concerns.

The health system in Liberia confronts massive challenges. When hospitals are non-existent or seriously under-staffed, when malaria is endemic and young mothers die during childbirth—it can be tempting to ask people suffering from trauma to simply “toughen up.”

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Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation

submitted by Denis Gilhooly

World Economic Forum
Prepared in collaboration with the Boston Consulting Group (BCG)

CLICK HERE - Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation

CLICK HERE - REPORT - Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation
(20 page .PDF report)

The Ebola outbreak in West Africa was a public health emergency of new proportions that presented unprecedented challenges for the international community. Aside from the significant social and economic impact it had on many West African countries, the epidemic also triggered a range of innovative, flexible partnership responses from businesses and civil society that complemented the channels of official assistance to affected countries.

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The contribution of Ebola viral load at admission and other patient characteristics to mortality in a Médecins Sans Frontières (MSF) Ebola Case Management Centre (CMC), Kailahun, Sierra Leone, June –October, 2014

m.jid.oxfordjournals.org - J Infect Dis. (2015) doi: 10.1093/infdis/jiv304 First published online: May 22, 2015

Abstract

This paper describes patient characteristics, including Ebola viral load, associated with mortality in an MSF Ebola case management centre.

Out of 780 admissions between June and October 2014, 525 (67%) were positive for Ebola with a known outcome. The crude mortality rate was 51% (270/525). Ebola viral load (whole blood sample) data was available on 76% (397/525) of patients. Univariate analysis indicated viral load at admission, age, symptom duration prior to admission and distance travelled to the CMC were associated with mortality (p value<0.05). The multivariable model predicted mortality in those with a viral load at admission greater than 10 million copies per millilitre (p value<0.05, Odds Ratio>10), aged 50 years or more (p value=0.08, Odds Ratio=2) and symptom duration prior to admission less than 5 days (p value=0.14). The presence of confusion, diarrhoea and conjunctivitis were significantly higher (p value<0.05) in Ebola patients who died.

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Guinea extends Ebola emergency measures

AFP     JUNE 6, 2015

CONAKRY--Ebola-hit Guinea has extended a health emergency declared in March until the end of June, citing the persistence of the deadly virus in the country, the presidency said on Saturday.


Workers walk at the Donka Ebola treatment center on May 2, 2015 in Conakry (AFP Photo/Cellou Binani)

The decision was taken on Friday by President Alpha Conde, the statement said, after he met his counterpart from Sierra Leone, Ernest Bai Koroma.

In August last year, Conde declared a health emergency for the whole of Guinea. Then on March 28, 2015, he decreed a "reinforced health emergency" for five provinces in the west and southwest of the West African country.

"Given the persistence of the epidemic... in parts of Guinea and Sierra Leone," Conde and Koroma decided "to extend the reinforced emergency measures in their countries until June 30, 2015", the Guinean presidency said.

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http://news.yahoo.com/guinea-extends-ebola-emergency-measures-201127353.html

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West Africa Struggles to Rebuild Its Ravaged Health-Care System

WALL STREET JOURNAL by Betsy McKay  June 4, 2015
HARPER, Liberia --The deadly disease may have receded, but it is still exacting a heavy toll. Run-down, poorly staffed and equipped health facilities allowed Ebola to explode.

 Since it was identified in early 2014, the epidemic has claimed the lives of 507 health-care workers in three West African countries, all of which already were short of medical professionals. The health-care system was so overwhelmed with Ebola victims that many other patients couldn’t receive care for malaria, heart disease or pregnancy complications. That bill is coming due.

“There are more people who are going to die from Ebola, but not have Ebola,” says Paul Farmer, a Harvard professor and co-founder of the Boston-based charity Partners in Health.

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Ebola Response Reveals the Need for New Models for Collaboration Between the Private and Public Sectors

A Report by the World Economic Forum and BCG Analyzes the Private Sector's Response to the Ebola Outbreak and Distills Lessons for Public-Private Partnerships in Future Health Crises

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BOSTON CONSULTING GROUP -MARKETWIRED June 4, 2014

CAPE TOWN, SOUTH AFRICA-- The private sector played an important role in the global response to the Ebola outbreak in West Africa not only by providing financial and in-kind donations but also by acting as a partner to support response activities.

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